OUR LAB IS NOW LOCATED AT IDIBELL (www.idibell.org)

The use of model organisms has reported great advances in understanding the fundamentals of human diseases. Particularly, researchers working with Caenorhabditis elegans have recently obtained two Nobel Prizes in Medicine and Physiology (2002 and 2006). The nematode C. elegans is a pioneer system for the use of RNA interference (RNAi) and a powerful model organism for addressing questions, in a rapid and inexpensive manner, in almost all aspect of biology. For example, we can make a double mutant strain in two weeks or we can screen hundreds of RNAi clones in just few weeks.

In our lab, we are taking advantage of genetics and genomics tools in C. elegans to better understand basic cellular mechanisms whose deregulation may produce disease in humans.